If you want to assign keyboard shortcuts to do the equivalent of Format::Change Case::Upper/Lower Case, go to Tools::Customise, choose the Keyboard tab, then assign a keyboard combo to Category = Format, Function = Lowercase or Uppercase (or the equivalents in your language, if you have the UI set for other than English).
This applies itself to selected text.
There are no preassigned shortcuts, so you can choose your own:
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